Meena started her career as a child artist in Telugu films and Tamil films. Meena acted with Rajinikanth and Kamal Haasan, and later became a star in her own right. Meena had hits with Muthu, Ejaman, Veera and Avvai Shanmughi. Following the release of her movies with Rajinikanth in Japan and their commercial success, Meenas popularity also rose in Japan.Meena has acted in almost all the south Indian languages like Tamil, Telugu, Malayalam, Kannada etc and opposite almost all the leading actors in these languages. Her first film as a child artist was Nenjangal with Sivaji Ganesan. Meena was in the film industry as the top heroine in Telugu and Tamil for almost one and a half decades successfully from the early 1990s. Meena often portrayed characters with uni dimensional personality with no negativity and shades of grey. Meena was also known to be limited as a glamorous actress though. Meena acted in a few glamorous roles like Maaman magal in Tamil opposite Sathyaraj and sneham kosan in Telugu opposite Megastar Chiranjeevi.